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Catalog_noBD-PB3752
Product_namePhospho-HSPA1A/HSPA1B(Y41) Antibody
Category抗原抗体
ApplicationsWB
ReactivityH
Size100μg/50μg
Price2000.00/1100.00
immunogenHUMAN
SpecificityThis HSPA1A/HSPA1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human HSPA1A/HSPA1B.
DilutionWB,1:500;
othernameHeat shock 70 kDa protein 1A/1B, Heat shock 70 kDa protein 1/2, HSP70-1/HSP70-2, HSP70.1/HSP70.2, HSPA1A, HSPA1, HSX70
IsotypeRabbit Ig
Background In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
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