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Catalog_noBDAB0056
Product_nameRecombinant Human ACE2 protein
Category冠状病毒产品
ApplicationsImmunogen
Size50ug/100ug/1mg
Price2400/3600/16000
SpecificityHomo sapiens (Human)
FormulationSupplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
SourceMammalian cells
Storage_stabilityUse a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt.
othernameACE-related carboxypeptidase,Angiotensin-converting enzyme homolog,Metalloprotease MPROT15
BackgroundAngiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
NotesACE2
descriptionRecombinant Human ACE2 is produced by Mammalian cells expression system and the target gene encoding Met1-Ser740 is expressed with C-His Tag
TypeN-10 His
Purity>90% as determined by SDS-PAGE
Molecular Weight86.8kDa
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