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Catalog_noBDAB0059
Product_nameRecombinant Human NRP1 protein
Category冠状病毒产品
ApplicationsImmunogen
Size50ug/100ug/1mg
Price1800/2800/8800
SpecificityHomo sapiens (Human)
FormulationSupplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
SourceE.coli
Storage_stabilityUse a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt.
othernameNeuropilin-1,Vascular endothelial cell growth factor 165 receptor,CD304.
BackgroundReceptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB . Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development). Regulates mitochondrial iron transport via interaction with ABCB8/MITOSUR.
NotesNRP1
descriptionRecombinant Human NRP1 is produced by E.coli expression system and the target gene encoding Phe22-Lys644 is expressed with His Tag
TypeHis tag
Purity>90% as determined by SDS-PAGE
Molecular Weight72.14 kDa
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