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Catalog_noBDAB0060
Product_nameRecombinant Human CD147 protein
Category冠状病毒产品
ApplicationsImmunogen
Size50ug/100ug/1mg
Price1800/2800/8800
SpecificityHomo sapiens (Human)
FormulationSupplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
SourceE.coli
Storage_stabilityUse a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt.
othername5F7 Protein, Human; Basigin Protein, Human; CD147 Protein, Human; EMMPRIN Protein, Human; M6 Protein, Human; OK Protein, Human; TCSF Protein, Human
BackgroundCD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
NotesCD147
descriptionRecombinant Human CD147 is produced by E.coli expression system and the target gene encoding Ala22-Ala207 is expressed with His Tag
TypeHis tag
Purity>90% as determined by SDS-PAGE
Molecular Weight22.59 kDa
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